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Parkin RBR E3 ubiquitin protein ligase (PARKIN), a key player in mitophagy

Similarly, the quinolinium containing parent analogue 1-MQ also lacked passive diffusion properties (Table 1), suggesting that the lipophilicity and drug-like permeability properties of analogues within the methylquinolinium series had to be improved via chemical modification

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Research applications encompass studies on cellular proliferation mechanisms, protein synthesis pathways, and metabolic regulation processes within controlled experimental environments